Hindered dissolution of fibrin formed under mechanical stress

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Hindered dissolution of fibrin formed under mechanical stress

BACKGROUND Recent data indicate that stretching forces cause a dramatic decrease in clot volume accompanied by gross conformational changes of fibrin structure. OBJECTIVE The present study attempts to characterize the lytic susceptibility of fibrin exposed to mechanical stress as a model for fibrin structures observed in vivo. METHODS AND RESULTS The relevance of stretched fibrin models was...

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ژورنال

عنوان ژورنال: Journal of Thrombosis and Haemostasis

سال: 2011

ISSN: 1538-7933

DOI: 10.1111/j.1538-7836.2011.04203.x